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About This Home

This 0-bedroom, 6-bathroom commercial at 101 Main Street in Dubuque, IA is listed for $1,290,000. Built in 1900, on a N/A lot.

Agent Description

Historic Redevelopment Opportunity - O'Neill Block | Dubuque, Iowa The O'Neill Block presents a rare 24,000+ SF mixed-use redevelopment opportunity in the heart of Dubuque's Old Main Historic District. The property features two fully built-out commercial spaces on the main floor, including a 4,062 SF restaurant/bar with a 6,092 SF finished lower-le

vel bar previously operating as 1st & Main, along with a 2,031 SF bar/retail space formerly known as Esther's Lounge (spaces are part of the sale but could also be leased). These spaces could continue as hospitality venues or be converted into office, retail, or other commercial uses.

The upper two floors offer more than 12,000 SF of redevelopment potential, ideal for apartments, condominiums, boutique offices, or creative workspaces, providing a true blank slate for a transformative mixed-use project. Located within the Dubuque Opportunity Zone, the property may qualify for Historic Tax Credits, Tax Increment Financing (TIF), and City of Dubuque housing and facade incentives.

The building sits in the center of major downtown investment, including the new John and Alice Butler College of Osteopathic Medicine developed by the University of Dubuque, expansion of the Dubuque Museum of Art, and continued redevelopment in the Historic Millwork District.

This site is in extremely close proximity to the Five Flags Center and nearby hotels including Hotel Julien Dubuque and Holiday Inn Dubuque/Galena, the location benefits from strong tourism, event traffic, and a growing downtown residential base. Positioned just one block from the Highway 20 / 61 / 151 corridor, the O'Neill Block offers outstanding

visibility and access, making it one of the most compelling historic redevelopment opportunities in downtown Dubuque. Seller will consider flexible financing options, including a potential land contract, for qualified buyers. Drone video:

Key Features

  • Built in 1900
  • 3 stories

Property Details

3 stories
6 full
1900

Amenities

A/C

Monthly Cost Estimate

$6,899/mo

20% down · 6.5% · 30 years

Principal$933
Interest$5,590
Insurance$376

Estimates only. Actual payments may vary.

Location

101 Main Street

Dubuque, IA 52001

Property Details

Flooring

ConcreteWood

Construction

Brick

Heating

Forced Air

Cooling

Central Air

Questions & Answers

This 0-bedroom, 6-bathroom commercial at 101 Main Street is listed at $1,290,000. The estimated monthly payment is $5,590 based on 20% down at 6.5% interest.

Key features include: Built in 1900, 3 stories.

This property is listed by Nancy Kann and can be reached at 5635807257 or nancyk@gronen.com.

NK

Nancy Kann

Agent at DBQ Property Group Inc.

(563) 580-7257

Listed by DBQ Property Group Inc.

MLS# 154128· Source: listhub· Updated 82 days ago

Copyright © 2026 East Central Iowa Association of Realtors. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

101 Main Street, Dubuque, IA 52001

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