# 101 Main Street, Dubuque, IA 52001

> **TL;DR:** 0bd/6ba commercial, $1,290,000, built 1900.
> A/C. Est. $5,590/mo. Listed 82 days.

## Property at a Glance

| Attribute | Value |
|-----------|-------|
| Price | $1,290,000 |
| Bathrooms | 6 full |
| Year Built | 1900 |
| Stories | 3 |
| Property Type | Commercial (Other) |
| Status | For Sale |
| Days on Market | 82 |

## Estimated Monthly Costs

| Category | Amount |
|----------|--------|
| Mortgage (20% down, 6.5%) | $5,590 |
| **Total** | **$5,590** |

## Key Amenities

- A/C

## Property Highlights

- Built in 1900
- 3 stories

## Description

### Agent Description
Historic Redevelopment Opportunity - O'Neill Block | Dubuque, Iowa The O'Neill Block presents a rare 24,000+ SF mixed-use redevelopment opportunity in the heart of Dubuque's Old Main Historic District. The property features two fully built-out commercial spaces on the main floor, including a 4,062 SF restaurant/bar with a 6,092 SF finished lower-level bar previously operating as 1st & Main, along with a 2,031 SF bar/retail space formerly known as Esther's Lounge (spaces are part of the sale but could also be leased). These spaces could continue as hospitality venues or be converted into office, retail, or other commercial uses. The upper two floors offer more than 12,000 SF of redevelopment potential, ideal for apartments, condominiums, boutique offices, or creative workspaces, providing a true blank slate for a transformative mixed-use project. Located within the Dubuque Opportunity Zone, the property may qualify for Historic Tax Credits, Tax Increment Financing (TIF), and City of Dubuque housing and facade incentives. The building sits in the center of major downtown investment, including the new John and Alice Butler College of Osteopathic Medicine developed by the University of Dubuque, expansion of the Dubuque Museum of Art, and continued redevelopment in the Historic Millwork District. This site is in extremely close proximity to the Five Flags Center and nearby hotels including Hotel Julien Dubuque and Holiday Inn Dubuque/Galena, the location benefits from strong tourism, event traffic, and a growing downtown residential base. Positioned just one block from the Highway 20 / 61 / 151 corridor, the O'Neill Block offers outstanding visibility and access, making it one of the most compelling historic redevelopment opportunities in downtown Dubuque. Seller will consider flexible financing options, including a potential land contract, for qualified buyers. Drone video:

## Location

- **Address:** 101 Main Street, Dubuque, IA 52001
- **County:** Dubuque

## Listing Agent

- **Name:** Nancy Kann
- **Brokerage:** DBQ Property Group Inc.
- **Phone:** 5635807257
- **Email:** nancyk@gronen.com

## Primary Photo

![101 Main Street - Primary Photo](http://lh.rdcpix.com/47e577258827895ce28aabe585ab1751l-f4288996492r.jpg)

*17 total photos available on [listing page](https://www.propertysimple.com/listing/101-main-street-dubuque-ia-52001-a154128)*

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**MLS#:** 154128 | **Updated:** 2026-06-18
**Source:** listhub

*Copyright © 2026 East Central Iowa Association of Realtors. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.*

[View on PropertySimple](https://www.propertysimple.com/listing/101-main-street-dubuque-ia-52001-a154128)

---

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  "description": "Historic Redevelopment Opportunity - O'Neill Block | Dubuque, Iowa The O'Neill Block presents a rare 24,000+ SF mixed-use redevelopment opportunity in the heart of Dubuque's Old Main Historic District. The property features two fully built-out commercial spaces on the main floor, including a 4,062 SF restaurant/bar with a 6,092 SF finished lower-level bar previously operating as 1st & Main, along with a 2,031 SF bar/retail space formerly known as Esther's Lounge (spaces are part of the sale but ",
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