About This Home

This 0-bedroom, 0-bathroom commercial at 221 N Main Street in Hannibal, MO is listed for $305,000 ($49 per sqft). Built in 1860, the home offers 6,216 sqft of living space on a 0.06 acres lot.

Key Features

  • Built in 1860
  • 0.06 acre lot
  • 3 stories

Property Details

3 stories
1860

Amenities

A/C
Listing Description

WELL BELOW APPRAISED VALUE!!! Excellent Opportunity to own your own building in Historic Downtown Hannibal. North Main Street attracts visitors and locals to shops, restaurants, and most of all the Mark Twain Boyhood Home and Museum properties. 221 North Main has had a substantial rehab around 2010.

Storefront restoration, new mechanical systems, roofing, interior remake, and lighting. Second floor has potential for additional retail square footage. 3 HVAC units, side entry off Bird Street and includes two private concrete parking pads. Over 4000 square feet of finished space. Be apart of Hannibal's tourist community. Location: Downtown, High Traffic, Retail Center

Monthly Cost Estimate

$1,631/mo

20% down · 6.5% · 30 years

Principal$221
Interest$1,322
Insurance$89

Estimates only. Actual payments may vary.

Location

221 N Main Street

Hannibal, MO 63401

City/Hannibal

Property Details

Construction

Brick

Parking

Driveway

Heating

Forced Air

Cooling

ElectricCentral Air

Questions & Answers

This 0-bedroom, 0-bathroom commercial at 221 N Main Street is listed at $305,000 ($49/sqft). The estimated monthly payment is $1,631 based on 20% down, a 30-year loan at 6.5% interest, estimated insurance.

Key features include: Built in 1860, 0.06 acre lot, 3 stories.

This property is listed by Sue-ann Westhoff.

SW

Sue-ann Westhoff

Agent at Prestige Realty, Inc.

Listed by Prestige Realty, Inc. · Broker phone: (573) 221-8171 x11 · Broker website

MLS# 25018821· Source: Mid America Regional Information Systems, Inc.· 8 days on PropertySimple

Copyright © 2026 Mid America Regional Information Systems, Inc. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

221 N Main Street, Hannibal, MO 63401

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